Engineering growing tissues
نویسندگان
چکیده
منابع مشابه
Engineering growing tissues.
Regenerating or engineering new tissues and organs may one day allow routine replacement of lost or failing tissues and organs. However, these engineered tissues must not only grow to fill a defect and integrate with the host tissue, but often they must also grow in concert with the changing needs of the body over time. We hypothesized that tissues capable of growing with time could be engineer...
متن کاملStresses in growing soft tissues.
Biochemical processes of tissue growth lead to production of new proteins, cells, and other material particles at the microscopic level. At the macroscopic level, growth is marked by the change of the tissue shape and mass. In addition, the appearance of the new material particles is generally accompanied by deformation and, consequently, stresses in the surrounding material. Built upon a micro...
متن کاملSimulation Modeling of Growing Tissues
Growing biological systems can be described as dynamical systems with a dynamical structure [8]. In such systems not only the values of variables characterizing system components, but also the number of components and the connections between them, may change over time. For example, in a developing plant, the numbers of branches, leaves and owers change as the plant grows, and the topology and f...
متن کاملMorphogenesis of growing soft tissues.
Recently, much attention has been given to a noteworthy property of some soft tissues: their ability to grow. Many attempts have been made to model this behavior in biology, chemistry, and physics. Using the theory of finite elasticity, Rodriguez has postulated a multiplicative decomposition of the geometric deformation gradient into a growth-induced part and an elastic one needed to ensure com...
متن کاملEngineering complex tissues.
Tissue engineering has emerged at the intersection of numerous disciplines to meet a global clinical need for technologies to promote the regeneration of functional living tissues and organs. The complexity of many tissues and organs, coupled with confounding factors that may be associated with the injury or disease underlying the need for repair, is a challenge to traditional engineering appro...
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ژورنال
عنوان ژورنال: Proceedings of the National Academy of Sciences
سال: 2002
ISSN: 0027-8424,1091-6490
DOI: 10.1073/pnas.192291499